Posts Tagged calcium d glucarate
@ GRAPEFRUIT, vs childhood
Posted by mmillr in PHYTONUTRIENTS: WHOLE PLANTS etc. on August 3, 2011
GRAPEFRUIT, “the flesh is acidic” just about summed it up for me for most of my life. As with some other fruits I never quite understood the attraction. Why would anyone put a half of one of these on a plate in front of them and proceed to squirt acid in their eyes by pressing into the [ bleep ] thing with a spoon? Then I got older. Lately I cant seem to get enough GRAPEFRUIT. I sit down and cant stop. Fortunately it doesn’t come in gallon size containers. Maybe I will branch out and try the un-skinned do it yourself type.
(and one of the best alcoholic beverages I have ever had was something called a “Big Pink” love that ‘masculine’ name, in a hip coffee shop called Muddy Waters up in Burlington Vermont. If they had lined up four or five of them I am not sure if or when I would have stopped. The ingredients were Campari, ginger ale, vodka, and GRAPEFRUIT JUICE!)
My early “raw” research notes follow below, more detailed discussion of the supporting studies will appear later.
–GRAPEFRUIT contains MONOTERPENES the effects of which have been described as “sweeping carcinogens out of the body”.
–some studies indicate that GRAPEFRUIT inhibits breast cancer cells in vitro
–inhibits cytochrome P450 3A4
–high in LYCOPENE and LIMINOIDS. (Who thinks that the ONLY place one can find LYCOPENE is in tomatoes? If you stay with these reports for awhile you’ll find there are several other places/foods than tomatoes!)
–contains GLUCARATES which help prevent breast cancer
–contains pectin
–increases antioxidants
–recent research proves that drinking GRAPEFRUIT JUICE provides protection against lung and colon cancer. Drinking three 6 ounce glasses of GRAPEFRUIT JUICE a day reduced the activity of an enzyme that activates cancer causing chemicals
–a flavonoid in GRAPEFRUIT called NARINGENIN helps repair damaged DNA in human prostate cancer cells
–GRAPEFRUIT derived LYCOPENE was shown to have an effect against androgen independent prostate cancer cells, in a concentration and time dependent manner. Same study determined that LUTEIN demonstrated a similar but slightly lesser response than LYCOPENE. No synergistic or additive effect observed between the two phytonutrients together.
–CALCIUM D GLUCARATE IS THE CALCIUM SALT OF D-GLUCARIC ACID. (found in highest concentrations in Oranges, APPLES, GRAPEFRUIT and CRUCIFEROUS VEGETABLES.) It (CDG) has been shown to inhibit beta-glucuronidase an enzyme. Elevated b-glucuronidase activity is associated with increased risk of various cancers, particularly those that are hormone related such as breast prostate and colon cancers.
–ten essential oils were tested against three laboratory human cancer cell lines. One of the secondary results was that the ten oils were more effective against prostate cancer than they were against lung or breast. One of the ten was GRAPEFRUIT and the prostate cancer cell line was the PC-3 androgen independent line.
–LYCOPENE is found in GRAPEFRUIT watermelon and papaya as well as tomatoes. It exhibits antioxidant and anti-cancer properties. …it has the potential to interfere with chemotherapy and radiation therapy.
–contains a compound called BERGAMOTTIN which reduces the activity of MMP (matrix metalloproteinase) which plays and important role in the ability of cancer cells to invade other tissues. Affected MMP-2, MMP-5 and MMP-9 expression. BERGAMOTTIN a phytochemical in GRAPEFRUIT inhibits tumor activity through its anti-invasive effects on tumor growth.
–multidrug resistance is often seen in cancer cells that have stopped reacting to chemotherapy. One specific chemical on the cancer cell walls is seen to be overexpressed, P-glycoprotein. NARINGIN the predominant flavone found in GRAPEFRUIT is able to “significantly lower P-glycoprotein expression”
–contains D-LIMONENE, one of the most common terpenes in nature (found in orange, lemon, mandarin, lime and GRAPEFRUIT citrus oils). (D-LIMONENE is also described as a solvent of cholesterol) It has also been used for heartburn and GERD, “has well established chemopreventive activity against many types of cancer”
It has already seen a PHASE 1 clinical trial with results showing a partial response in a patient with breast cancer. and “stable disease” for more than six months in several patients with colon cancer.
–the results of another study indicated that the consumption of GRAPEFRUIT or a compound LIMONIN found in GRAPEFRUIT ‘may’ help suppress colon cancer development
If I had known as an eight year old how wonderful GRAPEFRUIT was would I have liked it any better? No!
I was an eight year old! A kid! A smart ass! BUT YOU ARE OLDER WISER AND MORE MATURE! These foods were put on earth FOR YOU! They were created in God’s Kitchen, and you want man made cheese puffs? Artificial sweeteners? Artificial colorants? Preservatives? Chemicals?
martin
acidic, androgen independent, anti-invasive, antioxidant, apple, bergamottin, beta-glucuronidase, breast cancer, calcium d glucarate, cancer, CDG, chemoprotective, citrus, colon, cruciferous vegetable, d-glucaric acid, D-limonene, DNA, essential oil, expression, flavone, flavonoid, flesh, GERD, glucarate, glucarates, grapefruit, grapefruit juice, hormone, in vitro, lemon, lime, liminoid, liminoids, limonin, lung, lycopene, mandarin, matrix metalloproteinase, MDR, MMP, MMP-2, MMP-5, MMP-9, monoterpene, monoterpenes, multi-drug resistance, naringenin, oil, oils, orange, P-glycoprotein, PC 3, pectin, prostate, prostate cancer, terpene, tomato, tumor
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